After the death of Lorenzo de' Medici, Michelangelo returned to his father's home, and began to work upon a statue of Hercules, which is now lost. It used to stand in the Strozzi Palace until the siege of Florence in 1530, when Giovanni Battista della Palla bought it from the steward of Filippo Strozzi, and sent it into France as a present to the king.
The Magnificent left seven children by his wife Clarice, of the princely Roman house of the Orsini. The eldest, Piero, was married to Alfonsina, of the same illustrious family. Giovanni, the second, had already received a cardinal's hat from his kinsman, Innocent VIII. Guiliano, the third, was destined to play a considerable part in Florentine history under the title of Duke of Nemours. One daughter was married to a Salviati, another to a Ridolfi, a third to the Pope's son, Franceschetto Cybò. The fourth, Luisa, had been betrothed to her distant cousin, Giovanni de' Medici; but the match was broken off, and she remained unmarried.

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