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Levels of chemical contaminants in foods and feeds can originate from natural sources such as mycotoxins, which are toxic secondary metabolites produced by fungi on agricultural commodities in the field and during storage. More than 300 mycotoxins have been identified so far with widely different chemical structures and differing modes of action. The potential health risks to animals and humans posed by food- and feed-borne mycotoxin intoxication have been recognized by national and international organisations, which have addressed this problem by adopting regulatory limits for major mycotoxin classes and selected individual mycotoxins. The Romer Labs Guide to Mycotoxins is a timely reflection of the research progress related to the significance, sampling and determination of mycotoxins. In this respect, the Romer Labs Guide will not only provide a thorough introduction into the history of mycotoxins and mycotoxicoses, but will also discuss the chemistry and toxic effects of the most common mycotoxins. The book will also provide guidance for the development of proper sampling and sample preparation techniques to obtain representative samples for the subsequent analysis of the food and feed commodities to be checked for mycotoxins. The analytical part of the Romer Labs Guide to Mycotoxins covers proper extraction and clean-up procedures, separation and detection techniques including latest state-of-the-art rapid strip tests. Special emphasis is put on multi-toxin methods based on liquid chromatography coupled with mass spectrometry for the simultaneous determination of a wide variety of secondary fungal metabolites which allow for a comprehensive assessment of the wide range of mycotoxins humans and animals are exposed to.
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